I’m not really sure how it should be handled, to be perfectly honest. I don’t think they should deviate too far away from the original, but maybe a different setting (to meet modern game standards)…
If I had to suggest something, I’d say I liked the idea of having the original lines of alien grunts, but with the Gargantua running between them towards you, pushing them aside to get to you, but the screen fades out before he gets there. No sounds after fade.