Castle Anthrax would be. 
There is no proof where Portal takes place on the HL2 timeline. For all we know, GLaDOS could be protecting Chell from the county SWAT team, armed with a Houndeye unit and Adrian Shepard loaded into a canon. I personally think it would be cool for Portal’s timeline to overlap HL’s timeline.
That’s pretty well the point I was getting at, it’s been awhile since I played the game though, but I seem to recall there were some hints that Chell’s run through the Center occured during the Combine occupation (moreso than just dialogue from GlaDOS).
I’m looking forward to Portal 2 for sure though, it will definitely help put things into perspective. There is speculation that it’s going to be a prequel as Valve sent out a casting call for the role of Cave Johnson. Though I think it’s just as possible that Chell could encounter the Cave Johnson A.I., possibly in a quest to learn more about herself.
BTW, the one building that survived standing in Hiroshima was built by guys from Czechoslovakia (my home country) 
It was planned by him, but built by japanese
The nuke perpetuates the story. Before the server switch (I assume that is what happened), it was figured that the portals to Xen were opened by energy close to a resonance particle, the amount of energy in the area defining how big the portal could be, and how big the critter that could come through it was (Gargantua from the area with the big electric arc thingy, head crabs and hound eyes from malfunctioning overhead lights, etc.). Use a nuke, and you get a REALLY big portal, which the Combine used to take over the earth. And seeing as how a nuke is the best way to remove a biological contaminant (or anything really), it was a natural response. Use a nuke big enough to destroy the facility (several megatons), and you have a convenient ending that also perpetuates the story within the realms of it’s fiction.
PS I think the G-Man is playing all sides.
Well NO SHIT 
He has associated himself with:
-Balk Meas personel
-Marines
-GordAn
-Rebels
-Correct me if I’m wrong, but I think Aliens in some way.
Actually, the aliens part is about the only one you can be absolutely certain of. Everyone else just happened to be caught in the middle.
Would it count for all the scientists he talked to, the Marine CO, and Cubbage?
I don’t know if you caught the gist of my sarcasm here, but the nuking is a plot device, making this argument completely irrelevant. It’s like arguing that Legolas (being an elf, something that does not exist to our knowledge) could not not load and reload his bow at the rate he was during the movies because it is physically impossible.
You all realize in order to enjoy a piece of fiction one must suspend their disbelief. I’m pretty sure the lot of you enjoy Half-Life the proof being you are a member of these boards, yes?
Wait, I thought this was a Duke Nukem Forever Forum. This game isn’t really coming out, right?
Poor Reverend, yet another BM Voice of Reason™ doomed to be drowned out by the BM Babblings of Fools™.
That would be siggable IF I hadn’t already sigged one of your quotes.
Funny thing is half the members in each group are members of the other as well.
I just wish the OP would come back and let us know why he/she was so hung up on this that it was worth posting a thread about.
It’s no Philadelphia Project.
Because they wanted soldiers and scientists and aliens to live in harmony underground.
The should have watched Dr. Strangelove or How I Learned to Stop Worrying and Love the Bomb before wondering about that. The lack of nubile young women to be underground with would have foiled that whole idea.
"General “Buck” Turgidson: Doctor, you mentioned the ratio of ten women to each man. Now, wouldn’t that necessitate the abandonment of the so-called monogamous sexual relationship, I mean, as far as men were concerned?
Dr. Strangelove: Regrettably, yes. But it is, you know, a sacrifice required for the future of the human race. I hasten to add that since each man will be required to do prodigious… service along these lines, the women will have to be selected for their sexual characteristics which will have to be of a highly stimulating nature.
Ambassador de Sadesky: I must confess, you have an astonishingly good idea there, Doctor."
I assume that if he wanted aliens, soldiers, and scientists to live together, then there would also be Black Ops with them to… procreate.
Somehow I don’t think that is what Thomas More had in mind when he wrote his book.