Strider cannon on doctor Breen.
Jarate + Flamethrower on Dr. Breen.
Die, you suited bastard!
Om… impossible? Actually, I could probably do that since I have the TF2 swep pack for Garry’s Mod.
Black Hole Grenade on Alyx Vance.
One reason it wasn’t included in ep1.
I love the hopwire grenade.
Alien: Crowbar
Grunt: Crowbar
Cockroach: RPG
I’ve found it effective to use every explosive in my arsenal (mainly the grenade launcher) to dispose of the female assassins. This tactic wins on hard. Tripmines<3
Cockroach > Foot/Crowbar
Headcrab > Crowbar
Headcrab Zombie > Crowbar/Shotgun
Houndeye > Pistol
Vortigaunt > 357/Shotgun
Bullsquid > Shotgun
HGrunt > SMG/Shotgun
AGrunt > 357/RPG
Controller > 357
Tentacle > Rocket Engine
Female Assassins > Grenade
Nihilanth > Gauss/Crowbar
I use the crossbow most of the time, actually.
It actually fills the same general role as the Pulse Rifle, in case you didn’t know.
Headcrab - Crowbar
Zombie - Crowbar
Houndeye - Pistol/Shotgun
Vortigaunt - Shotgun/MP5
Bullsquid - Shotgun
Soldier - MP5
Controller - Shotgun/Pistol
Female Assassin - MP5
Ichthyosaur - Crossbow, duh.
Vehicles - Grenades/RPG
I always try to complete the game with just crowbar, pistol, shotgun, and SMG, unless I need to use a specific weapon, such as RPG for tanks, or crossbow for the ichy.
I would think the crossbow fills the same general role as the… crossbow. But that’s just me.
Headcrab - Crowbar
Zombie - Crowbar
Houndeye - Crowbar
Vortigaunt - Crowbar
Bullsquid - Crowbar
Soldier - Crowbar
Controller - Crowbar
Female Assassin - Crowbar
Ichthyosaur - Crowbar
Vehicles - Crowbar
WHAT???
:meh:
Headcrab - Crowbar
Zombie - Shotgun
Houndeye - Pistol/Gauss
Vortigaunt - Shotty
Bullsquid - Crowbar
Soldier - Snark
Controller - Ignore
Female Assassin - Ignore
Ichthyosaur - Crossbow/Crowbar.
Vehicles - Bunnyhop past it
Nihilanth - Pistol
I like how you choose to ignore certain creatures. 
Vortigaunt hands on freeman.
Fap for him.:fffuuu::fffuuu::fffuuu:
HL1
Headcrab-Pistol/Shotgun
Zombie-Shotgun
Houndeye-Pistol
Bullsquid-Shotgun/Mp5
Vort-Magnum/Shotgun
Barnacle-Shotgun/Crowbar
Hgrunt-Magnum/Crossbow/Tau Cannon/Mp5
Tentacle-Rocket engine
Garg-Generator/Mortars/Rocket launcher, Tau Cannon, Mp5 grenade,Satchel charges, and Tripmines
Agrunt-Magnum/Crossbow/Mp5 grenade/Gluon
Snark- Mp5
Controller-Ignore
Baby Headcrab-Shotgun
Gonarch-All my shotgun and mp5 ammo
Nihilanth-Gluon and rocket launcher
HL2
CP-Pistol
Soldier-Smg/Shotgun/Ar2/Gravy gun
Elite- Magnum/Shotgun/Ar2/Gravy gun
Headcrab-Crowbar/Gravy gun
Zombie-Shotgun/Gravy gun
Fast Headcrab-Crowbar
Fast Zombie-Shotgun
Poison Headcrab-Whichever gun I’m holding at the moment
Posion Zombie-Ar2 ball
Antlion-Shotgun/Buggy Tau cannon
Antlion Guard-Ar2/Shotgun/Smg grenade/Rocket launcher
Manhack-Crowbar/Smg
Strider-Smg grenade/Ar2 ball/Rocket launcher
Gunship-Rocket launcher/Smg grenade
Shameless bump. I still wana hear those weapon/enemy combos.
That’s okay. We’ll supply the shame.