There are some nice and often very small but effective fixes available through the Steam Workshop which in my opinion are good enough to be added to an upstream update:
Tripmine Aquiring Sound Fix
No Sprint Sound - removes the sprint sound, which is very annoying with alyways sprint enabled. Another idea would be to disable this sound only when always sprinting is enabled.
Emergency Flare Texture Edit/Fix
Scientist Shirt Retexture
Weapons Sound Sync Fix
Hivehand Acquisition Fix (what many players have been waiting for a while)
Blast Pit Lighting Fix
Lambda Core Teleport lighting fix