Bit of a weird one:
When encountering the Gluon gun, picking it up caused my whole computer to freeze. This could be repeated reliably 3-4 times in a row and happened literally just as the gun was picked up.
The odd thing is, I then picked it up by accident (trying to open the door so I could kill the bullsquid) and no crash. Just thought I’d report it though.
Let me know if you need computer info.