Looks like you’ve been in a great hurry to post a reply. That much hurry so you forgot to read OP message:
2OP: Try rolling back drivers to latest stable release for your videocard (304.x series for most nVIDIA cards), remove all and any custom settings you had applied in nVIDIA CP and/or third-party tools like nVIDIA Inspector. Most importantly: turn off Ambient Occlusions, turn off FXAA, turn off Adaptive Vsync, set vsync to be forced off by default, set antialiasing to be controlled by application, set anisotropic filtering to also be controlled by application and set power mode to be “Use maximum performance”.
Then, edit command line parameters for BMS and all “-dxlevel 98” there. Start it up once (it should reset all the renderer settings and screen resolution to safe defaults), configure output resolution to your personal preferences, then go into advanced gfx settings dialog and there chose not to use AA, not to use Aniso (i.e. set filtering to “Trilinear”), use HDR, do not use motion blur, do not use vsync and max out all other settings. Then quit the game and remove “-dxlevel” parameter you had added to game command line startup parameters.
Make sure you have no dxwrapper apps running around like MSI Afterburner, DXoverrider and various types of SMAA/FXAA injectors. And turn off Steam In-Game Community in global steam preferences.
Then start up the game and check if stutters persist. If they are: proceed with budget panel like described here: https://forums.blackmesasource.com/showthread.php?p=494535#post494535
If not: start to enabling back settings like steam community and Co one by one testing the game after enabling each of them. You would either end up with the problem-causing setting or would get the game working normally with all the things turned back on.
P.S. And, first of all, check the value of the in-game cvar mat_queue_mode, it should be set to 0. If it’s set to 1 or 2 - you’d end up with huge amount of stutter/jitter and frequent crashes here and there.