What he said.
Except that he meant Episode 3. 
Off the top of my head, I’d say the most anticipated games for me are;
NFS Shift – Bought to us by the guys who made GTR2, and promising some suspiciously simulation like driving for a NFS game.
rFactor 2 – Some really tasty looking improvements on what is already one of the most expansive race simulators
Black Mesa – The odd one out a bit, bit pretty obviously gonna be the most polished thing out there.
Link?
I’m with Going Postal on Prototype.
Also Assassin’s Creed 2, Diablo 3, and BM: S. In that order. 
BTW:
Black Mesa
Diablo III
Half-Life 2: Episode 3
0 A.D.
(no specific order)
- Halo 3: ODST (Orbital Drop Shock Troopers)
- Mass Effect 2
- Half Life 2: Episode Three
Assasin’s Creed 2
Prototype
Uh…
That’s it for now.
Prototype
Diablo 3
HL:E3
Red Dead Redemption
Oh and ummm… Hi. I’m new.
welcome to the forums B)
fix’d.
bioshock 2, i loved the first one
the obviouses , thi4f
oh , and gothic 4
Sims 3, Halo 3 ODST, HL2ep3, Balc Meas, and Fallout 3 (Its been out, but Ive never got around to buying it)
Battlefield: Bad Company 2 (PC version is said to be made from scratch, not a port)
HL2:EP3
Black Mesa (This is my most anticipated game of the year)
Wolfenstien
Red Dead Redemption
Red Faction
Black Mesa (Do I even need a reason?)
ArmA II (Dear god…this game looks incredible)
Operation Flashpoint 2 (Hardy har har. I’m a realism fag.)
MW2 (Not realistic, but still tons of fun to kill across the map with a MP5SD)
Borderlands (4 Player Co-op, customizable vehicles, RPG/FPS elements, and customizable weapons. I’m in.)
Okay guys, cut it with the Black Mesa/Half-Life 2: Episode 3 shit. If you’ve registered on the fourms, you’re excited for those two. Now let’s be a little more creative, shall we?
Most Looking Forward To:
Halo: ODST: I feel lonely when I’m on the fourms. Everyone here seems to hate Halo for some reason (actually, I know exactly why they don’t like Halo. They repeat it over and over again. “nutin spesial bout it un like cod4 cod4 iz da shit mofofucker lololzz!!!”)
Bionic Commando: Bionic Commando: Rearmed was simply amazing. I don’t care what the reviews say, I’m renting this game (and maybe even buy it eventually) and I’m going to have a blast! Besides, the multiplayer demo was awesome!
Bioshock 2: The first one was good, but collected dust real fast after I beat it. Bioshock 2 now has multiplayer, so hopefully it won’t suffer like the last one did.
Battlefield: Bad Company 2: I loved the first one, but I never got to try out the multiplayer (I borrowed a copy from my friend, and we had to play in the living room without internet.)
Fallout: New Vegas: More Fallout is always a good thing (except another BHoS spin-off.)
Kinda-Sorta-Looking Forward To:
Postal III: Postal 2 was simply a guilty pleasure. Postal III looks like it’ll be Postal 2 and more! Also, it uses the source engine! You know what that means right? Garry’s Mod!
Call of Duty 6: Modern Warfare 2: Despite my anti-CoD claims, there was a time that I actually liked Call of Duty 4. The best part about these games is that they’re released so close to Christmas that I can just ask for it and get a free copy on Christmas morning!
I agree.
this.
Portal 2.