In Residue Processing I ran into two issues:
#1 If you save the guard from the headcrabs and barnacles early in the level, he will be stuck in an idle pose and won’t respond to interaction. He should be able to assist you if you save him. After saving the guard he ran into the doorway and wouldn’t move. Talking to him and running into him wouldn’t move him. I needed to progress through the door so I was forced to kill him.
#2 I replayed a particular sequence on the conveyor belt multiple times (by reloading a save) and my fps dropped from 280 to 40 (and below) for a brief period every time. The fps drop happened in the exact same spot each time for a few seconds. It seems like it was related to a missing sound file.
C2A2B:
#3 I encountered an issue on an earlier map (C2A2B) where a grunt was stuck in a wall which caused a level design error. I forgot the “getpos” command at that point but it was around the time when a security guard told Freeman that it sounded like there was an ambush ahead and I think he mentioned something about a dance card.